ABSTRACT
Gestational trophoblastic disease comprises a spectrum of interrelated conditions originating from the placenta. Malignant gestational trophoblastic disease refers to lesions that have the potential for local invasion and metastasis. This compromises many histological entities including hydatidiform moles, invasive moles, gestational choriocarcinomas, and placental site trophoblastic tumors. Before the advent of sensitive assays for human chorionic gonadotropin (hCG) and efficacious chemotherapy, the morbidity and mortality from gestational trophoblastic disease were substantial. Currently, with sensitive quantitative assays for beta-hCG and current approaches to chemotherapy, most women with malignant trophoblastic disease can be cured. We present a case of malignant gestational trophobalstic tumor with serum beta-hCG concentration over 1million IU/L that metastaze to the lungs and have a hyperthyroidism, but negative urine hCG testing. We report a case with a brief review of literatures.
Subject(s)
Female , Humans , Pregnancy , Choriocarcinoma , Chorionic Gonadotropin , Drug Therapy , Gestational Trophoblastic Disease , Hydatidiform Mole, Invasive , Hyperthyroidism , Lung , Mortality , Neoplasm Metastasis , Placenta , Trophoblastic Tumor, Placental Site , TrophoblastsABSTRACT
Angioleiomyoma is a rare benign soft tissue tumor that originates from smooth muscle cells and contains thick-walled blood vessels. Few cases of angioleiomyoma have been described at sites other than the extremities and head. The female genital tract is rarely involved. We have experienced a case of retroperitoneal angioleiomyoma with abnormal MRI and CT findings, which was confused with ovarian malignancy.